The gunman was found with a Quran in his vehicle and was wearing what sources described as "Islamic" clothing during the attack.
A U.S. official said the conflict with Iran is now expected to stretch on for weeks, though no clear timeline has been given by Trump.
Videos shared on social media showed a large police presence at the scene, with a shirtless person lying dead in the street.
Reza Pahlavi urged Iran's military to abandon the regime after Khamenei's death, positioning himself in a potential transition.
The anchor read out a statement describing Ali Khamenei as a deeply revered Islamic religious figure, saying his "long dream of martyrdom became true."
Tt was not confirmed where Khamenei died, but a photo of his body was shown to Israeli Prime Minister Benjamin Netanyahu, a senior Israeli official revealed.
The attack came as Iran launched retaliatory strikes across the Middle East following a joint United States–Israel assault on Tehran earlier in the day.
Officials say the 86-year-old leader was not inside the compound — or even in Tehran — when the attack happened and was later relocated to a secure, undisclosed location.
Officials added that many others were wounded, though early casualty figures varied as details continued to emerge.
Pakpour was named the new commander of Iran's Revolutionary Guard in June 2025, stepping into the role after his predecessor, Hossein Salami, was killed in Israeli airstrikes.
A North Dakota judge finalized a $345 million judgment against Greenpeace over protests tied to the Dakota Access Pipeline.
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Targets included military sites in Tehran, areas near Supreme Leader Ayatollah Ali Khamenei's offices and the presidential compound, Isfahan, Qom, Karaj and Kermanshah.
President Trump said US forces began major combat operations in Iran as Israel launched missile strikes and Tehran retaliated.
Trump raised the prospect of military action against Iran as an Omani mediator said a nuclear deal could be reached soon.