In a study conducted in 41 countries, the researchers have revealed that breast cancer rates among women are on the rise globally. The research, published in the journal The Lancet Global Health, found that in higher-income nations rates of breast cancer in premenopausal women are increasing, while postmenopausal breast cancer is increasing more rapidly in lower-income countries.
Although breast cancer is thought to be a disease of the developed world, almost 50 percent of breast cancer cases and 58 percent of deaths occur in less developed countries, according to the World Health Organization (WHO).
"To our knowledge, this is the first study to investigate the global rates and trends of pre- and postmenopausal breast cancer," said study researcher Miranda Fidler-Benaoudia from the University of Calgary in Canada.
Trend in Higher-Income Countries Concerning
Fidler-Benaoudia added further, "Distinguishing between pre- and postmenopausal breast cancer allowed us to uncover different trends, which could be important for tailoring prevention efforts and curbing the future breast cancer burden worldwide."
Although the study provides evidence of an increase in breast cancer rates in women of all ages, the increase in premenopausal breast cancer in higher-income countries is particularly concerning, according to the researchers.
Premenopausal breast cancer was significantly increasing in 20 out of 44 populations, they said. Postmenopausal breast cancer is significantly increasing in 24 out of the 44 populations, most notably in countries undergoing transitions from lower to higher-income status.
Adoption of Early Screening Methods Vital
The research team said that this could be a result of these countries adopting a more Western lifestyle that includes unhealthy behaviors that increase breast cancer risk such as lower levels of physical activity and increased alcohol consumption.
Adopting early screening procedures, which are common in higher-income countries, could play a part as well, by identifying more cases early on. The study highlights the inequities in cancer mortality worldwide, showing that about 47 percent of women diagnosed with premenopausal breast cancer in less developed countries will die, compared to only 11 percent in the most developed countries.
Postmenopausal breast cancer saw a fatality rate of 56 percent in less developed nations compared to 21 percent in their more developed counterparts. "Early diagnosis and access to treatment remain key to combating breast cancer in low- and middle-income countries," the study authors wrote.